The Effect of Pre- And Post-Operative Prognostic Values on Patient Survival in Patients With Stomach Cancer

Research Article

Özet

Objective: Prognostic values ​​in gastric cancer have been frequently investigated in the literature. While some studies have yielded similar results, others have been the subject of debate. In our study, we examined several preoperative and postoperative parameters to evaluate factors that may influence prognosis. This study retrospectively evaluated the prognostic factors and investigated their impact on postoperative patient survival.

Methods: This retrospective study examined the clinical records, pathological results, and operative reports of 180 patients who underwent elective surgery for gastric cancer at the General Surgery Clinic of Kocaeli University Faculty of Medicine Research and Practice Hospital between January 2017 and December 2020.

Results: The impact of different surgical procedures on patient survival: 61.2% of patients who underwent total gastrectomy, 68.4% who underwent subtotal gastrectomy, and 43.7% who underwent other surgical procedures survived. Among patients with Stage 0+1 disease, 83.8% survived, whereas this rate was lower in patients with other stages (p = 0.007). These results suggest that tumor metastasis plays an important role in treatment effectiveness and patient survival (p = 0.004). The presence of lymph node metastases significantly impacts cancer patients' survival (p = 0.004). The rate of metastases in dissected lymph nodes was also significant in multivariate analysis (p = 0.041).

Conclusion: In this study, when evaluated univariately, four values (stage, presence of lymph node metastasis, serosa invasion, and metastasis rate in the dissected lymph node) were predictive of prognosis, whereas, when analyzed multivariately, only one value (metastasis rate in the dissected lymph node) was significant.

Objective: Prognostic values ​​in gastric cancer have been frequently investigated in the literature. While some studies have yielded similar results, others have been the subject of debate. In our study, we examined several preoperative and postoperative parameters to evaluate factors that may influence prognosis. This study retrospectively evaluated the prognostic factors and investigated their impact on postoperative patient survival.

Methods: This retrospective study examined the clinical records, pathological results, and operative reports of 180 patients who underwent elective surgery for gastric cancer at the General Surgery Clinic of Kocaeli University Faculty of Medicine Research and Practice Hospital between January 2017 and December 2020.

Results: The impact of different surgical procedures on patient survival: 61.2% of patients who underwent total gastrectomy, 68.4% who underwent subtotal gastrectomy, and 43.7% who underwent other surgical procedures survived. Among patients with Stage 0+1 disease, 83.8% survived, whereas this rate was lower in patients with other stages (p = 0.007). These results suggest that tumor metastasis plays an important role in treatment effectiveness and patient survival (p = 0.004). The presence of lymph node metastases significantly impacts cancer patients' survival (p = 0.004). The rate of metastases in dissected lymph nodes was also significant in multivariate analysis (p = 0.041).

Conclusion: In this study, when evaluated univariately, four values (stage, presence of lymph node metastasis, serosa invasion, and metastasis rate in the dissected lymph node) were predictive of prognosis, whereas, when analyzed multivariately, only one value (metastasis rate in the dissected lymph node) was significant.