Stem Cell Therapy in Cardiovascular Diseases
Review Article
DOI:
https://doi.org/10.5281/zenodo.10404484Keywords:
Cardiovascular, Diseases, Stem CellAbstract
The majority of heart diseases, especially myocardial infarction, have high mortality and morbidity. Surgical operation and transplantation are common treatment methods for these diseases. Stem cells are specialised cells with high regenerative ability and the ability to transform into different cells and tissues. In the past years, it was argued that there was no regeneration in the heart, but stem cell therapy has emerged as a new hope in cardiovascular system diseases with the discovery that cardiomyocytes renew themselves and that there are cells with telomerase activity that show c-Kit, Sca-1 stem cell markers. Experimental studies show that especially in myocardial infarction model regeneration is observed in the damaged area after stem cell transplantation. As a result, stem cell therapy has started to be used for therapeutic purposes in our country, but since it is a new method, it has not yet gained widespread use. In addition, it is thought that more scientific studies on cardiac stem cells are needed both experimentally and clinically.
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